Measles surveillance activities in the Metropolitan Area of Milan

In Italy, the transmission of measles is still endemic, and 7,919 cases were reported to the National Surveillance System between January 2017 and December 2018.
Aim of this study is to report the results of the measles surveillance activities in the Metropolitan City of Milan from March 2017 to December 2018, and to evaluate the surveillance performance WHO indicators.The Local Health Units (LHUs) carried out case investigations and collected specimens to send to the EpiSoMI Lab (Subnational Reference Laboratory, SRL) of the University of Milan for cases/outbreaks confirmation and genotyping performed according to the WHO Guidelines.
Overall, 610 suspected measles cases were reported by the surveillance system of the Metropolitan City of Milan. A total of 439 out of 540 cases with adequate specimens were laboratory-confirmed by molecular and/or serological assays. Two-hundred and thirty-six cases were notified as sporadic and 203 as related to 94 outbreaks.
The most confirmed cases were aged 15-39 years, almost all not vaccinated. Overall, 282 cases were genotype D8 and 118 genotype B3.The evaluation of a set of indicators to monitor the quality of surveillance activities demonstrated the proficiency of the EpiSoMI Lab.

L002

B7739-5 5 mg
EUR 139

L002

B7739-50 50 mg
EUR 638

L002

B2859-1
EUR 109

L002

B2859-5
EUR 240

OG-L002

B1580-5.1 10 mM (in 1mL DMSO)
EUR 166
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

OG-L002

9406-25
EUR 697

OG-L002

9406-5
EUR 229

OG-L002 HCl

A8766-25 25 mg
EUR 514
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

OG-L002 HCl

A8766-5 5 mg
EUR 166
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

ThioStar? Fluorescent Thiol Substrate, 250UG

L002-250UG 250UG
EUR 613

ThioStar? Fluorescent Thiol Substrate, 500UG

L002-500UG 500UG
EUR 1075

ThioStar? Fluorescent Thiol Substrate, 50UG

L002-50UG 50UG
EUR 207

Lincomycin Hydrochloride USP

L002-1G 1 g
EUR 83

Lincomycin Hydrochloride USP

L002-5G 5 g
EUR 270

DiagNano Gold Labeled Silica Particles, 4 μm

DNG-L002 10 mL
EUR 694

DiagPoly Plain Fluorescent Polystyrene Particles, Yellow, 0.1-0.3 µm

DNM-L002 2 mL
EUR 657

Recombinant Obelin, 100UG

L001-100UG 100UG
EUR 384

Recombinant Obelin, Calcium Chelator Free, 100UG

L001C-100UG 100UG
EUR 384

Anti-CD314 Antibody [CX5], Unconjugated-100ug

QAB100-100ug 100ug
EUR 182

Anti-CD4 Antibody [OKT4], Unconjugated-100ug

QAB11-100ug 100ug
EUR 123

Anti-CD8a Antibody [Hit8a], Unconjugated-100ug

QAB20-100ug 100ug
EUR 149

Anti-CD11c Antibody [N418], Unconjugated-100ug

QAB23-100ug 100ug
EUR 157

Anti-CD11c Antibody [3.9], Unconjugated-100ug

QAB24-100ug 100ug
EUR 141

Anti-CD11b Antibody [ICRF44], Unconjugated-100ug

QAB25-100ug 100ug
EUR 141

Anti-CD19 Antibody [1D3], Unconjugated-100ug

QAB28-100ug 100ug
EUR 141

Anti-CD3 Antibody [17A2], Unconjugated-100ug

QAB3-100ug 100ug
EUR 141

Anti-CD25 Antibody [PC61.5], Unconjugated-100ug

QAB34-100ug 100ug
EUR 123

Anti-CD25 Antibody [BC96], Unconjugated-100ug

QAB35-100ug 100ug
EUR 141

Anti-CD27 Antibody [O323], Unconjugated-100ug

QAB36-100ug 100ug
EUR 141

Anti-CD28 Antibody [CD28.2], Unconjugated-100ug

QAB37-100ug 100ug
EUR 141

Anti-CD45.1 Antibody [A20], Unconjugated-100ug

QAB42-100ug 100ug
EUR 157

Anti-CD45.2 Antibody [104], Unconjugated-100ug

QAB43-100ug 100ug
EUR 141

Anti-CD45RO Antibody [UCHL1], Unconjugated-100ug

QAB44-100ug 100ug
EUR 141

Anti-CD45RA Antibody [HI100], Unconjugated-100ug

QAB45-100ug 100ug
EUR 141

Anti-CD45 Antibody [HI30], Unconjugated-100ug

QAB46-100ug 100ug
EUR 141

Anti-CD3 Antibody [OKT3], Unconjugated-100ug

QAB5-100ug 100ug
EUR 149

Anti-CD3 Antibody [UCHT1], Unconjugated-100ug

QAB6-100ug 100ug
EUR 141

Anti-CD8a Antibody [2.43], Unconjugated-100ug

QAB61-100ug 100ug
EUR 149

Anti-CD3 Antibody [Hit3a], Unconjugated-100ug

QAB7-100ug 100ug
EUR 141

Anti-KLRG1 Antibody [2F1], Unconjugated-100ug

QAB74-100ug 100ug
EUR 141

Anti-CD161 Antibody [PK136], Unconjugated-100ug

QAB78-100ug 100ug
EUR 141

Anti-CD4 Antibody [GK1.5], Unconjugated-100ug

QAB8-100ug 100ug
EUR 123

Anti-CD32 Antibody [2.4G2], Unconjugated-100ug

QAB87-100ug 100ug
EUR 141

Anti-CD28 Antibody [37.51], Unconjugated-100ug

QAB99-100ug 100ug
EUR 149

Anti-c-Myc Antibody [9E10], Unconjugated-100ug

QAB102-100ug 100ug
EUR 216

Anti-CD4 Antibody [RPA-T4], Unconjugated-100ug

QAB12-100ug 100ug
EUR 123

Anti-CD8a Antibody [53-6.7], Unconjugated-100ug

QAB16-100ug 100ug
EUR 131

Anti-CD8a Antibody [RPA-T8], Unconjugated-100ug

QAB19-100ug 100ug
EUR 149

Anti-CD3e Antibody [145-2C11], Unconjugated-100ug

QAB2-100ug 100ug
EUR 123

Anti-CD45 Antibody [30-F11], Unconjugated-100ug

QAB40-100ug 100ug
EUR 149

Anti-CD80 Antibody [16-10A1], Unconjugated-100ug

QAB50-100ug 100ug
EUR 182

Anti-CD86 Antibody [GL-1], Unconjugated-100ug

QAB51-100ug 100ug
EUR 157

Anti-CD161 Antibody [HP-3G10], Unconjugated-100ug

QAB60-100ug 100ug
EUR 157

Rat IgG1 Isotype Control (HRPN), Untagged-100ug

QAB63-100ug 100ug
EUR 131

Rat IgG2a Isotype Control (2A3), Untagged-100ug

QAB64-100ug 100ug
EUR 131

Mouse IgG2a Isotype Control (C1.18.4), Untagged-100ug

QAB66-100ug 100ug
EUR 141

Anti-IL-4 Antibody [11B11], Unconjugated-100ug

QAB81-100ug 100ug
EUR 149

Anti-FCER1A Antibody [MAR-1], Unconjugated-100ug

QAB91-100ug 100ug
EUR 182

Recombinant Human Procalcitonin Protein, Native, Human-100ug

QDX51-100ug 100ug
EUR 318

Recombinant Human APOA1 Protein, Native, Human-100ug

QDX57-100ug 100ug
EUR 377

Recombinant Human STX12 Protein, His, E.coli-100ug

QP13630-100ug 100ug
EUR 1261

Recombinant Human STX1A Protein, Untagged, E.coli-100ug

QP13633-100ug 100ug
EUR 1261

Recombinant Human SYCE3 Protein, His, E.coli-100ug

QP13654-100ug 100ug
EUR 1261

Recombinant Human SYT11 Protein, His, E.coli-100ug

QP13658-100ug 100ug
EUR 1261

Recombinant Human SYT4 Protein, His, E.coli-100ug

QP13661-100ug 100ug
EUR 1261

Recombinant Human TEF Protein, His, E.coli-100ug

QP13717-100ug 100ug
EUR 1261

Recombinant Human THG1L Protein, His, E.coli-100ug

QP13742-100ug 100ug
EUR 1261

Recombinant Human Thyroglobulin Protein, Untagged, Native.-100ug

QP13748-100ug 100ug
EUR 201

Recombinant Human TMED10 Protein, His, E.coli-100ug

QP13761-100ug 100ug
EUR 1261

Recombinant Human TNC Protein, Untagged, E.coli-100ug

QP13766-100ug 100ug
EUR 201

Recombinant Human TPGS2 Protein, His, E.coli-100ug

QP13792-100ug 100ug
EUR 1261

Recombinant Human TRAPPC2 Protein, His, E.coli-100ug

QP13803-100ug 100ug
EUR 1261

Recombinant Human TRAPPC4 Protein, His, E.coli-100ug

QP13806-100ug 100ug
EUR 1261

Recombinant Human TSR2 Protein, His, E.coli-100ug

QP13830-100ug 100ug
EUR 1261

Recombinant Human TSSK2 Protein, His, E.coli-100ug

QP13832-100ug 100ug
EUR 1261

Recombinant Human TTC33 Protein, His, E.coli-100ug

QP13838-100ug 100ug
EUR 1261

Recombinant Human USE1 Protein, His, E.coli-100ug

QP13910-100ug 100ug
EUR 1261

Recombinant Human USP46 Protein, His, E.coli-100ug

QP13912-100ug 100ug
EUR 1261

Recombinant Human VAMP1 Protein, Untagged, E.coli-100ug

QP13915-100ug 100ug
EUR 201

Recombinant Human VAV1 Protein, His, E.coli-100ug

QP13927-100ug 100ug
EUR 1261

Recombinant Human VPS26A Protein, His, E.coli-100ug

QP13942-100ug 100ug
EUR 1261

Recombinant Human XG Protein, His, E.coli-100ug

QP13971-100ug 100ug
EUR 1261

Recombinant Human YARS2 Protein, His, E.coli-100ug

QP13981-100ug 100ug
EUR 1261

Recombinant Human YOD1 Protein, His, E.coli-100ug

QP13984-100ug 100ug
EUR 1261

Recombinant Human ZADH2 Protein, His, E.coli-100ug

QP13989-100ug 100ug
EUR 1261

Recombinant Human ZG16 Protein, His, E.coli-100ug

QP13995-100ug 100ug
EUR 1261

Recombinant Zika Ectodomain Protein, Untagged, Insect-100ug

QP13996-100ug 100ug
EUR 1859

Recombinant Human ZMAT3 Protein, His, E.coli-100ug

QP14002-100ug 100ug
EUR 1261

Recombinant Mouse LIF Protein, Untagged, E.coli-100ug

QP4235-100ug 100ug
EUR 608

Recombinant Human BDNF Protein, Untagged, E.coli-100ug

QP5220-100ug 100ug
EUR 708

Recombinant Human TGFB3 Protein, Untagged, E.coli-100ug

QP5237-100ug 100ug
EUR 717

Recombinant Human IL25 Protein, Untagged, E.coli-100ug

QP5273-100ug 100ug
EUR 490

Recombinant Human PDGFA Protein, Untagged, E.coli-100ug

QP5283-100ug 100ug
EUR 536

Recombinant Human FGF8 Protein, Untagged, E.coli-100ug

QP5301-100ug 100ug
EUR 490

Recombinant Human FGF4 Protein, Untagged, E.coli-100ug

QP5343-100ug 100ug
EUR 490

Recombinant Human GDF11 Protein, Untagged, E.coli-100ug

QP5369-100ug 100ug
EUR 536
A well-done investigation of cases and outbreaks by the surveillance local system, in a timely manner, in order to notify and investigate suspected cases and to laboratory confirm or discard cases is fundamental to reduce morbidity, to prevent further virus transmission and to achieve measles elimination.