Measles surveillance activities in the Metropolitan Area of Milan

In Italy, the transmission of measles is still endemic, and 7,919 cases were reported to the National Surveillance System between January 2017 and December 2018.
Aim of this study is to report the results of the measles surveillance activities in the Metropolitan City of Milan from March 2017 to December 2018, and to evaluate the surveillance performance WHO indicators.The Local Health Units (LHUs) carried out case investigations and collected specimens to send to the EpiSoMI Lab (Subnational Reference Laboratory, SRL) of the University of Milan for cases/outbreaks confirmation and genotyping performed according to the WHO Guidelines.
Overall, 610 suspected measles cases were reported by the surveillance system of the Metropolitan City of Milan. A total of 439 out of 540 cases with adequate specimens were laboratory-confirmed by molecular and/or serological assays. Two-hundred and thirty-six cases were notified as sporadic and 203 as related to 94 outbreaks.
The most confirmed cases were aged 15-39 years, almost all not vaccinated. Overall, 282 cases were genotype D8 and 118 genotype B3.The evaluation of a set of indicators to monitor the quality of surveillance activities demonstrated the proficiency of the EpiSoMI Lab.

L002

B2859-5
EUR 240

L002

B7739-10 10 mg
EUR 186

L002

B7739-25 25 mg
EUR 367

L002

B7739-5 5 mg
EUR 139

L002

B7739-50 50 mg
EUR 638

L002

HY-100671 25mg
EUR 302

OG-L002

B1580-25 25 mg
EUR 512
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

OG-L002

B1580-5 5 mg
EUR 168
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

OG-L002

B1580-5.1 10 mM (in 1mL DMSO)
EUR 166
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

OG-L002

9406-25
EUR 697

OG-L002

9406-5
EUR 229

OG-L002 HCl

A8766-25 25 mg
EUR 514
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

OG-L002 HCl

A8766-5 5 mg
EUR 166
Description: OG-L002 is a specific and potent inhibitor of lysine (K)-specific demethylase 1A (LSD1) with IC50 value of 20 nM [1].LSD1 is a flavin-dependent monoamine oxidase, which can demethylate lysines.

Recombinant Obelin, 100UG

L001-100UG 100UG
EUR 384

DiagNano Gold Labeled Silica Particles, 4 μm

DNG-L002 10 mL
EUR 694

DiagPoly Plain Fluorescent Polystyrene Particles, Yellow, 0.1-0.3 µm

DNM-L002 2 mL
EUR 657

Lincomycin Hydrochloride USP

L002-1G 1 g
EUR 83

ThioStar? Fluorescent Thiol Substrate, 250UG

L002-250UG 250UG
EUR 613

ThioStar? Fluorescent Thiol Substrate, 500UG

L002-500UG 500UG
EUR 1075

ThioStar? Fluorescent Thiol Substrate, 50UG

L002-50UG 50UG
EUR 207

Lincomycin Hydrochloride USP

L002-5G 5 g
EUR 270

Recombinant Obelin, Calcium Chelator Free, 100UG

L001C-100UG 100UG
EUR 384

Anti-CD314 Antibody [CX5], Unconjugated-100ug

QAB100-100ug 100ug
EUR 182

Anti-CD4 Antibody [OKT4], Unconjugated-100ug

QAB11-100ug 100ug
EUR 123

Anti-CD8a Antibody [Hit8a], Unconjugated-100ug

QAB20-100ug 100ug
EUR 149

Anti-CD11c Antibody [N418], Unconjugated-100ug

QAB23-100ug 100ug
EUR 157

Anti-CD11c Antibody [3.9], Unconjugated-100ug

QAB24-100ug 100ug
EUR 141

Anti-CD11b Antibody [ICRF44], Unconjugated-100ug

QAB25-100ug 100ug
EUR 141

Anti-CD19 Antibody [1D3], Unconjugated-100ug

QAB28-100ug 100ug
EUR 141

Anti-CD3 Antibody [17A2], Unconjugated-100ug

QAB3-100ug 100ug
EUR 141

Anti-CD25 Antibody [PC61.5], Unconjugated-100ug

QAB34-100ug 100ug
EUR 123

Anti-CD25 Antibody [BC96], Unconjugated-100ug

QAB35-100ug 100ug
EUR 141

Anti-CD27 Antibody [O323], Unconjugated-100ug

QAB36-100ug 100ug
EUR 141

Anti-CD28 Antibody [CD28.2], Unconjugated-100ug

QAB37-100ug 100ug
EUR 141

Anti-CD45.1 Antibody [A20], Unconjugated-100ug

QAB42-100ug 100ug
EUR 157

Anti-CD45.2 Antibody [104], Unconjugated-100ug

QAB43-100ug 100ug
EUR 141

Anti-CD45RO Antibody [UCHL1], Unconjugated-100ug

QAB44-100ug 100ug
EUR 141

Anti-CD45RA Antibody [HI100], Unconjugated-100ug

QAB45-100ug 100ug
EUR 141

Anti-CD45 Antibody [HI30], Unconjugated-100ug

QAB46-100ug 100ug
EUR 141

Anti-CD3 Antibody [OKT3], Unconjugated-100ug

QAB5-100ug 100ug
EUR 149

Anti-CD3 Antibody [UCHT1], Unconjugated-100ug

QAB6-100ug 100ug
EUR 141

Anti-CD8a Antibody [2.43], Unconjugated-100ug

QAB61-100ug 100ug
EUR 149

Anti-CD3 Antibody [Hit3a], Unconjugated-100ug

QAB7-100ug 100ug
EUR 141

Anti-KLRG1 Antibody [2F1], Unconjugated-100ug

QAB74-100ug 100ug
EUR 141

Anti-CD161 Antibody [PK136], Unconjugated-100ug

QAB78-100ug 100ug
EUR 141

Anti-CD4 Antibody [GK1.5], Unconjugated-100ug

QAB8-100ug 100ug
EUR 123

Anti-CD32 Antibody [2.4G2], Unconjugated-100ug

QAB87-100ug 100ug
EUR 141

Anti-CD28 Antibody [37.51], Unconjugated-100ug

QAB99-100ug 100ug
EUR 149

Anti-c-Myc Antibody [9E10], Unconjugated-100ug

QAB102-100ug 100ug
EUR 216

Anti-CD4 Antibody [RPA-T4], Unconjugated-100ug

QAB12-100ug 100ug
EUR 123

Anti-CD8a Antibody [53-6.7], Unconjugated-100ug

QAB16-100ug 100ug
EUR 131

Anti-CD8a Antibody [RPA-T8], Unconjugated-100ug

QAB19-100ug 100ug
EUR 149

Anti-CD3e Antibody [145-2C11], Unconjugated-100ug

QAB2-100ug 100ug
EUR 123

Recombinant Human HMGA2 Protein, His, E.coli-100ug

QP12281-100ug 100ug
EUR 1261

Recombinant Human HSP20 Protein, Untagged, E.coli-100ug

QP12326-100ug 100ug
EUR 1315

Recombinant Human HSPB8 Protein, Untagged, E.coli-100ug

QP12335-100ug 100ug
EUR 1315

Recombinant Virus HTNV Protein, GST, E.coli-100ug

QP12359-100ug 100ug
EUR 218

Recombinant Human IER3 Protein, His, E.coli-100ug

QP12370-100ug 100ug
EUR 1261

Recombinant Human IGFBP6 Protein, His, E.coli-100ug

QP12383-100ug 100ug
EUR 1261

Recombinant Human INHBC Protein, His, E.coli-100ug

QP12447-100ug 100ug
EUR 1261

Recombinant Human ITGB1BP3 Protein, His, E.coli-100ug

QP12463-100ug 100ug
EUR 1261

Recombinant Human JAM3 Protein, His, E.coli-100ug

QP12468-100ug 100ug
EUR 1261

Recombinant other JEV Protein, His, E.coli-100ug

QP12471-100ug 100ug
EUR 218

Recombinant Human JSRP1 Protein, His, E.coli-100ug

QP12473-100ug 100ug
EUR 1261

Recombinant Human KCTD4 Protein, His, E.coli-100ug

QP12481-100ug 100ug
EUR 1261

Recombinant Human KCTD5 Protein, His, E.coli-100ug

QP12482-100ug 100ug
EUR 1261

Recombinant Human KLK3 Protein, Untagged, Human-100ug

QP12506-100ug 100ug
EUR 1161

Recombinant Human KXD1 Protein, His, E.coli-100ug

QP12520-100ug 100ug
EUR 1261

Recombinant Human LAGE3 Protein, His, E.coli-100ug

QP12524-100ug 100ug
EUR 1261

Recombinant Human LAMTOR4 Protein, His, E.coli-100ug

QP12534-100ug 100ug
EUR 1261

Recombinant Rat LCN2 Protein, His, E.coli-100ug

QP12546-100ug 100ug
EUR 1261

Recombinant Rat LDHA Protein, His, Insect-100ug

QP12549-100ug 100ug
EUR 1261

Recombinant Human LGALS13 Protein, Untagged, E.coli-100ug

QP12559-100ug 100ug
EUR 201

Recombinant other lldD Protein, His, E.coli-100ug

QP12578-100ug 100ug
EUR 1261

Recombinant Human LPCAT1 Protein, His, E.coli-100ug

QP12580-100ug 100ug
EUR 1261

Recombinant Canine LRG1 Protein, Untagged, Canine-100ug

QP12582-100ug 100ug
EUR 1061

Recombinant Human LSM12 Protein, His, E.coli-100ug

QP12590-100ug 100ug
EUR 1261

Recombinant Human LTA4H Protein, His, E.coli-100ug

QP12594-100ug 100ug
EUR 1261

Recombinant Human MAGEA6 Protein, His, E.coli-100ug

QP12625-100ug 100ug
EUR 1261

Recombinant Human MAGEA8 Protein, His, E.coli-100ug

QP12626-100ug 100ug
EUR 1261

Recombinant Human MAGEB10 Protein, His, E.coli-100ug

QP12627-100ug 100ug
EUR 1261

Recombinant Human MECOM Protein, His, E.coli-100ug

QP12667-100ug 100ug
EUR 1261

Recombinant Mouse MESDC2 Protein, His, E.coli-100ug

QP12681-100ug 100ug
EUR 1261

Recombinant Human MET Protein, Untagged, Insect-100ug

QP12683-100ug 100ug
EUR 1061

Recombinant Human METTL21A Protein, His, E.coli-100ug

QP12688-100ug 100ug
EUR 1261

Recombinant Human MINA Protein, His, E.coli-100ug

QP12698-100ug 100ug
EUR 1261

Recombinant Human MOCS2 Protein, His, E.coli-100ug

QP12715-100ug 100ug
EUR 1261

Recombinant other MoeX Protein, His, E.coli-100ug

QP12716-100ug 100ug
EUR 218

Recombinant Human MPPED2 Protein, His, E.coli-100ug

QP12723-100ug 100ug
EUR 1261

Recombinant Human MSI2 Protein, His, E.coli-100ug

QP12738-100ug 100ug
EUR 1261

Recombinant Human MUCL1 Protein, His, E.coli-100ug

QP12751-100ug 100ug
EUR 1261

Recombinant Human MUSTN1 Protein, His, E.coli-100ug

QP12755-100ug 100ug
EUR 1261

Recombinant Human Myo Protein, Untagged, E.coli-100ug

QP12775-100ug 100ug
EUR 201

Recombinant Human NAIF1 Protein, His, E.coli-100ug

QP12786-100ug 100ug
EUR 1261

Recombinant Human NANOGP8 Protein, Untagged, E.coli-100ug

QP12788-100ug 100ug
EUR 1261

Recombinant Human NDUFA5 Protein, His, E.coli-100ug

QP12812-100ug 100ug
EUR 1261

Recombinant Human NDUFS2 Protein, His, E.coli-100ug

QP12818-100ug 100ug
EUR 1261

Recombinant Human NELFE Protein, His, E.coli-100ug

QP12828-100ug 100ug
EUR 1261

Recombinant Human NEUROG3 Protein, His, E.coli-100ug

QP12832-100ug 100ug
EUR 1261

Recombinant Human NFE2L2 Protein, His, E.coli-100ug

QP12834-100ug 100ug
EUR 1261

Recombinant Human NHEJ1 Protein, His, E.coli-100ug

QP12842-100ug 100ug
EUR 1261

Recombinant Mouse NNMT Protein, His, E.coli-100ug

QP12862-100ug 100ug
EUR 1261

Recombinant Human NOP16 Protein, His, E.coli-100ug

QP12864-100ug 100ug
EUR 1261

Recombinant Human NRBF2 Protein, His, E.coli-100ug

QP12878-100ug 100ug
EUR 1261

Recombinant Human NREP Protein, His, E.coli-100ug

QP12879-100ug 100ug
EUR 1261

Recombinant Human NUDC Protein, His, E.coli-100ug

QP12897-100ug 100ug
EUR 1261

Recombinant Human ORM1 Protein, Untagged, Human-100ug

QP12931-100ug 100ug
EUR 1261

Recombinant Human OXLD1 Protein, His, E.coli-100ug

QP12941-100ug 100ug
EUR 1261

Recombinant Human PARD6B Protein, His, E.coli-100ug

QP12962-100ug 100ug
EUR 1261

Recombinant Human PCSK1N Protein, His, E.coli-100ug

QP12981-100ug 100ug
EUR 1261

Recombinant Human PDCL Protein, His, E.coli-100ug

QP12988-100ug 100ug
EUR 1261

Recombinant Human PDHX Protein, His, E.coli-100ug

QP12994-100ug 100ug
EUR 1261

Recombinant other PfHSP70 Protein, Untagged, E.coli-100ug

QP13018-100ug 100ug
EUR 218

Recombinant E.coli phrB Protein, His, E.coli-100ug

QP13046-100ug 100ug
EUR 1261

Recombinant Human PIH1D2 Protein, His, E.coli-100ug

QP13053-100ug 100ug
EUR 1261

Recombinant Human PKNOX1 Protein, His, E.coli-100ug

QP13067-100ug 100ug
EUR 1261

Recombinant Human PNPT1 Protein, His, E.coli-100ug

QP13086-100ug 100ug
EUR 1261

Recombinant Human POLD4 Protein, His, E.coli-100ug

QP13092-100ug 100ug
EUR 1261

Recombinant Human PPP1CC Protein, His, E.coli-100ug

QP13122-100ug 100ug
EUR 1261

Recombinant Human PREP Protein, His, E.coli-100ug

QP13136-100ug 100ug
EUR 1261

Recombinant Human PRKACA Protein, Untagged, Insect-100ug

QP13140-100ug 100ug
EUR 2213

Recombinant Human PRND Protein, His, E.coli-100ug

QP13149-100ug 100ug
EUR 1261

Recombinant Human PRNP Protein, His, E.coli-100ug

QP13150-100ug 100ug
EUR 1261

Recombinant Rat PVALB Protein, Untagged, E.coli-100ug

QP13219-100ug 100ug
EUR 2458

Recombinant Human RAMP3 Protein, His, E.coli-100ug

QP13260-100ug 100ug
EUR 1261

Recombinant Human RFXANK Protein, His, E.coli-100ug

QP13304-100ug 100ug
EUR 1261

Recombinant Human RGS14 Protein, His, E.coli-100ug

QP13307-100ug 100ug
EUR 1261

Recombinant Human RPL26L1 Protein, His, E.coli-100ug

QP13346-100ug 100ug
EUR 1261

Recombinant Human RPS19 Protein, His, E.coli-100ug

QP13353-100ug 100ug
EUR 1261

Recombinant Mouse RSPO1 Protein, His, Insect-100ug

QP13365-100ug 100ug
EUR 1261

Recombinant Human RTCA Protein, His, E.coli-100ug

QP13368-100ug 100ug
EUR 1261

Recombinant Human RYBP Protein, His, E.coli-100ug

QP13379-100ug 100ug
EUR 1261

Recombinant Mouse S100A10 Protein, His, E.coli-100ug

QP13387-100ug 100ug
EUR 1261

Recombinant Rat S100G Protein, His, E.coli-100ug

QP13406-100ug 100ug
EUR 2259

Recombinant Human SCP2D1 Protein, His, E.coli-100ug

QP13436-100ug 100ug
EUR 1261

Recombinant Human SDHAF1 Protein, His, E.coli-100ug

QP13441-100ug 100ug
EUR 1261

Recombinant Human SEC61B Protein, His, E.coli-100ug

QP13447-100ug 100ug
EUR 1261

Recombinant Human SELPLG Protein, His, E.coli-100ug

QP13451-100ug 100ug
EUR 1261

Recombinant Human SERTAD1 Protein, His, E.coli-100ug

QP13470-100ug 100ug
EUR 1261

Recombinant Human SERTAD2 Protein, His, E.coli-100ug

QP13471-100ug 100ug
EUR 1261

Recombinant Human SETD7 Protein, Untagged, E.coli-100ug

QP13473-100ug 100ug
EUR 201

Recombinant Human SIKE1 Protein, His, E.coli-100ug

QP13502-100ug 100ug
EUR 1261

Recombinant Human SIL1 Protein, His, E.coli-100ug

QP13505-100ug 100ug
EUR 1261

Recombinant Human SORBS3 Protein, His, E.coli-100ug

QP13559-100ug 100ug
EUR 1261

Recombinant Human SRA1 Protein, His, E.coli-100ug

QP13589-100ug 100ug
EUR 1261

Recombinant Human SSR1 Protein, His, E.coli-100ug

QP13594-100ug 100ug
EUR 1261

Recombinant Human SSSCA1 Protein, His, E.coli-100ug

QP13597-100ug 100ug
EUR 1261

Recombinant Human STK17B Protein, His, E.coli-100ug

QP13618-100ug 100ug
EUR 1261

Recombinant Human STX12 Protein, His, E.coli-100ug

QP13630-100ug 100ug
EUR 1261

Recombinant Human STX1A Protein, Untagged, E.coli-100ug

QP13633-100ug 100ug
EUR 1261
A well-done investigation of cases and outbreaks by the surveillance local system, in a timely manner, in order to notify and investigate suspected cases and to laboratory confirm or discard cases is fundamental to reduce morbidity, to prevent further virus transmission and to achieve measles elimination.